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李麗玉助理教授

 

Education:

1992-1999   MD, Chang Gung University School of Medicine

 

Employment Record :

1998-1999        Intern, Chang Gung Memorial Hospital, Taoyuan

1999-2002        Resident, Department of Pathology, Chang Gung

                         Memorial Hospital, Taoyuan

2002-2003        Chief Resident, Department of Pathology, Chang

                         Gung Memorial Hospital, Taoyuan

2003-present    Attending physician, Department of

                         Pathology, Chang Gung Memorial Hospital,

                         Taoyuan

 

License: Taiwan medical License: No. 030611

Certified anatomic pathology board in Taiwan: No. 296

部定講師:講字第0九六八二四號

部定助理教授:助理字第035532

                              (REG.NO:035532)

 

Professional Affiliations:

  Member of the Taiwan Society of Pathology

  Member of the Taiwan Division of the International

  Academy of Pathology

  Member of the Taiwan Society of Clinical Cytology

 

E-mail address:

r22068@cgmh.org.tw

 

Research Interest:

  1. Head and neck cancer:

--- Study and identify the metastasis-associated protein in head and neck cancer

--- Searching for plasma tumor marker in head neck cancer by proteomic methods and the correlation study with clinicopathological status

--- Study and identify precancer-associated protein in head and neck cancer

  1. Breast: morphological and immunophenotypic analysis of breast carcinomas with basal differentiation
  2. Stomach: different protein expressions in the intestinal- type and signet-ring cell type adenocarcinoma
  3. Female genital tract: the histopathologic change of vaginal biopsy after vaginal repair
  4. Gastrointestinal stromal tumor of small intestine and stomach: a clinicopathological and immunohistochemical analysis

 

Research Project:

  1. 以擴展範圍的16排多切面電腦斷層掃描及氟18去氧葡萄糖正子掃描來評估口腔麟狀上皮癌. NSC94-2314-B-182A-109, 2005/8/1~2006/7/31
  2. Identification of potential biomarkers for NPC based on the preliminary
    results of cDNA microarray – from a global genomic viewpoint. CMRPG360211, CMRPG360212, and CMRPG360213, 2007/1/1~2009/12/31
  3. Identification of potential roles of proteases and protease inhibitors in the local invasion and distant metastasis of NPC cells based on the preliminary results of cDNA microarrays.  NMRPG366211 ,  NMRPG366212 , and NMRPG366213 , (NSC96-2314-B-182A-109-MY3), 2007/8/1~2010/7/31
  4. 整合型Integrity study of epidemiology and translational research of head neck cancer:頭頸癌之流行性 CMRPG160341, CMRPG160342, and CMRPG160343, 2007/10/1~2010/9/30
  5. 整合型Integrity study of epidemiology and translational research of head neck cancer子計畫三:以蛋白(I, II,III).  CMRPG360841, CMRPG360842, and CMRPG360843, 2007/10/1~2010/9/30
  6. Analysis of esterified F- and D/E-ring isoprostanes and neuroprostanes, and lipid-soluble antioxidants in brain stem tissues from rats following experimental subarachnoid hemorrhage.  NMRPG170552, and NMRPG170553 (NSC97-2320-B-182-012-MY3),  2008/8/1~2011/7/31
  7. 頭頸癌中,細胞伴隨分子(molecular chaperon)對放射治療抵抗性之生物資訊及臨床表徵之綜合研究(長清計劃) CMRPG390421, 2010/01/01~2010/12/31
  8. 幹細胞標記在肢端型惡性黑色瘤的表現及其與腫瘤轉移和臨床結果的關係 CMRPG290351, 2010/07/01~2011/06/30
  9. Evaluation of the potential of microRNAs in circulation as novel biomarkers of oral cancer. (評估血液中微小RNA作為口腔癌新穎生物標誌之可能性)  NMRPG396091, NMRPG396092, and NMRPG396093 (NSC99-2314-B-182A-034-MY3), 2010/8/1~2013/7/31
  10. 結合生物標誌和分子影像預估M0鼻咽癌病人是否有潛在遠端轉移病灶.( NSC 101-2314-B-182A-079-), 2012/08/01~ 2014/7/31
  11. 探討核仁磷酸蛋白B23對於雌激素接受器ERα的調控及其生理意義. NMRPG3C0301 ( NSC 102-2320-B-182A-013-), 2013/08/01~ 2014/7/31
  12.  Correlation among circulating tumor cells in Human Papillomavirus-positive oropharyngeal cancer patients and clinical outcomes. (人類乳突病毒陽性之口咽癌患者之周邊循環腫瘤細胞偵測、分離與臨床關聯性研究) NMRPD1E1011, NMRPD1E1012, and NMRPD1E1013 (MOST 104-2314-B-182 -031 -MY3), 2015/08/01~2018/07/31
  13. The feasibility of circulating tumor cells isolation for transcriptomes and genome-wide associated analysis in postsurgically high-risk oral cavity cancer patients and its clinical significance. (高風險口腔癌患者術後周邊循環腫瘤細胞偵測、分離與表現基因體及全基因體分析之可行性與臨床關聯性研究) NMRPG3E6141, NMRPG3E6142, and NMRPG3E6143 (MOST 104-2314-B-182A-073 -MY3), 2015/08/01~2018/07/31
  14. Systemic approach to discover radio-resistant biomarkers and develop a radio-sensitizing platform for head-neck cancer. (以系統性研究方式,來開發頭頸癌放療抗性之分子標誌與放療增敏劑平台) NMRPG3E6171, NMRPG3E6172, and NMRPG3E6173 (MOST 104-2314-B-182A-088 -MY3), 2015/08/01~2018/07/31
  15. Exonic mutation signature of head-neck cancer: integrative analyses of transcriptomic and genomic profiles by microarray and next generation sequencing techniques. (結合轉錄體與基因體之研究,來尋找與頭頸癌相關之表達子突變特徵) NMRPD1E0661, NMRPD1E0662, and NMRPD1E0663 (MOST 104-2320-B-182 -023 -MY3), 2015/08/01~2018/07/31
  16. To investigate the mechanism and the physiological significance of drug therapy in endometrial cancer. (探討子宮內膜癌之藥物治療的調控與生理意義) NMRPG3F0081 (MOST 105-2320-B-182A-005 -), 2016/08/01~2017/07/31

 

Publications:

A. Articles:

  1. Lee LY, Hsu HL, Chen HM, Hsueh C. Ductal adenocarcinoma of the pancreas with huge cystic degeneration: A lesion to be distinguished from pseudocyst and mucinous cystadenocarcinoma.  Int J Surg Pathol. 2003;11(3):235-239 

(SCI; IF=0.782; Surgery 158/200)。

  1. Wang AC, Lee LY, Lin CT, Chen JR. A histologic and immunohistochemical analysis of defective vaginal healing after continence taping procedures: a prospective case-controlled pilot study.  Am J Obstet Gynecol. 2004;191(6):1868-1874

(SCI; IF=4.681; Obstetrics & Gynecology 3/80)。

  1. Yang CH, Wu JYJ, Lee LY, Kuo MC, Lee SC, Yu KH. Adult-onset Still’s disease associated with hemophagocytic Syndrome: A case report and literature review.  Rheumatol. 2005;19(2):69-78
  2. Lee LY, Kang CJ, Hsieh YY, Hsueh S. Diagnosis of nodal Langerhans cell histiocytosis by fine needle aspiration cytology.  Chang Gung Med J. 2005;28(10):735-739
  3. Chang KP, Lee LY, Yeh AR, Dai TS, Hao SP. Endoscopic CO2 laser surgery for an atypical carcinoid tumor of the epiglottis masquerading as a supraglottic cyst.  Head Neck. 2005;27(11):1004-1007

(SCI; IF=2.76; Otorhinolaryngology 3/43)。

  1. Wu CM, Lee YS, Wang TH, Lee LY, Kong WH, Chen ES, Wei ML, Liang Y, Hwang TL. Identification of differential gene expression between intestinal and diffuse gastric cancer using a cDNA microarray.  Oncol Rep. 2006;15(1):57-64

(SCI; IF=2.486; Oncology 130/213)。

  1. Hsieh YY, Shen WS, Lee LY, Wu TL, Ning HC, Sun CF. Long-term changes in trace elements in patients undergoing chronic hemodialysis.  Biol Trace Elem Res. 2006;109(2):115-122

(SCI;  IF=1.798;  Biochemistry & molecular biology 220/289)。

  1. HO KC, Yen TC, Ng SH, Chang JT, Lee LY, Liao CT, Kang CJ.   Negative Impact of 18F-FDG PET for Restaging in a Case of Recurrent Buccal Cancer.  Annals of Nuclear Medicine and Science. 2006;19(2):115-118
  2. Liao CT, Chang JT, Wang HM, Ng SH, Hsueh C, Lee LY, Lin CH, Chen IH, Kang CJ, Huang SF, Tsai MF, Yen TC. Surgical outcome of T4a and resected T4b oral cavity cancer.  Cancer. 2006;15;107(2):337-344 (SCI; IF=5.649; Oncology 26/213)。
  3. Liao CT, Wang HM, Hsieh LL, Chang JT, Ng SH, Hsueh C, Lee LY, Lin CH, Chen IH, Kang CJ, Huang SF, Yen TC. Higher distant failure in young age tongue cancer patients.  Oral Oncol. 2006;42(7):718-725 (SCI; IF=4.286; Dentistry, oral surgery & medicine 3/91)。
  4. Liao CT, Wang HM, Ng SH, Yen TC, Lee LY, Hsueh C, Wei FC, Chen IH, Kang CJ, Huang SF, Chang JT. Good tumor control and survivals of squamous cell carcinoma of buccal mucosa treated with radical surgery with or without neck dissection in Taiwan.  Oral Oncol. 2006;42(8):800-809

(SCI; IF=4.286; Dentistry, oral surgery & medicine 3/91 )

  1. Ng SH, Yen TC, Chang JT, Chan SC, Ko SF, Wang HM, Lee LY, Kang CJ, Wong AM, Liao CT. Prospective study of [18F]fluorodeoxyglucose positron emission tomography and computed tomography and magnetic resonance imaging in oral cavity squamous cell carcinoma with palpably negative neck.  J Clin Oncol. 2006;20;24(27):4371-4376

(SCI; IF=20.982; Oncology 5/213)。

  1. Kuo WL, Lee LY, Wu CM, Wang CC, Yu JS, Liang Y, Lo CH, Huang KH, Hwang TL. Differential expression of claudin-4 between intestinal and diffuse-type gastric cancer.  Oncol Rep. 2006;16(4):729-734

(SCI; IF=2.486; Oncology 130/213)。

  1. Wu TJ, Lee LY, Yeh CN, Wu PY, Chao TC, Hwang TL, Jan TT, Chen MF. Surgical treatment and prognostic analysis for gastrointestinal stromal tumors (GISTs) of the small intestine: Before the era of Imatinib Mesylate.  BMC Gastroenterol. 2006;6 (1):29:1-8

(SCI; IF=2.101; Gastroenterology & hepatology 53/79)

  1. Chen YJ, Chang JT, Lee LY, Wang HM, Liao CT, Chiu CC, Chen PJ, Cheng AJ. DSG3 is overexpressed in head neck cancer and is a potential molecular target for inhibition of oncogenesis.  Oncogene. 2007;18;26:467-476

(SCI; IF= 7.932; Oncology 15/213)。

  1. Liao CT, Ng SH, Chang JT, Wang HM, Hsueh C, Lee LY, Tsao CK, Chen WH, Chen IH, Kanh CJ, Huang SF, Yen TC. T4b oral cavity cancer below the mandibular notch is resectable with a favorable outcome.  Oral Oncol. 2007;43(6):570-579

(SCI; IF=4.286; Dentistry, oral surgery & medicine 3/91)

  1. Liao CT, Chang JT, Wang HM, Ng SH, Hsueh C, Lee LY, Lin CH, Chen IH, Huang SF, Cheng AJ, Yen TC. Survival in squamous cell carcinoma of the oral cavity: differences between pT4 N0 and other stage IVA categories.  Cancer. 2007;110(3):564-571

(SCI; IF=5.649; Oncology 26/213)。

  1. Chang JT, Chan SH, Lin CY, Lin TY, Wang HM, Liao CT, Wang TH, Lee LY, Cheng AJ. Differentially expressed genes in radioresistant nasopharyngeal cancer cells: gp96 and GDF15.  Mol Cancer Ther. 2007;6(8):2271-2279

(SCI; IF= 5.579; Oncology 27/213)。

  1. Liao CT, Kang CJ, Chang JT, Wang HM, Ng SH, Hsueh C, Lee LY, Lin CH, Cheng AJ, Chen IH, Huang SF, Yen TC. Survival of second and multiple primary tumors in patients with oral cavity squamous cell carcinoma in the betel quid chewing area.  Oral Oncol. 2007;43(8):811-819

(SCI; IF=4.286; Dentistry, oral surgery & medicine 3/91)。

  1. Liao CT, Wang HM, Chang JT, Ng SH, Hsueh C, Lee LY, Lin CH, Chen IH, Huang SF, Yen TC. Analysis of risk factors for distant metastases in squamous cell carcinoma of the oral cavity.  Cancer. 2007;20;110(7):1501-1508

(SCI; IF=5.649; Oncology 26/213)。

  1. Liao CT, Chang JT, Wang HM, Ng SH, Hsueh C, Lee LY, Lin CH, Chen IH, Huang SF, Cheng AJ, Yen TC. Salvage therapy in relapsed squamous cell carcinoma of the oral cavity: How and when?  Cancer. 2008;112(1):94-103

(SCI; IF=5.649; Oncology 26/213)。

  1. Ngan KW, Jung SM, Lee LY, Chuang WY, Yeh CJ, Hsieh YY. Immunohistochemical expression of OCT4 in primary central nervous system germ cell tumours.  J Clin Neurosci. 2008;15(2):149-152

(SCI; IF=1.387; Clinical neurology 151/193)。

  1. Liao CT, Chang JT, Wang HM, Ng SH, Hsueh C, Lee LY, Lin CH, Chen IH, Huang SF, Cheng AJ, Yen TC. Analysis of risk factors of predictive local tumor control in oral cavity cancer.  Ann Surg Oncol. 2008;15(3):915-922

(SCI; IF=3.655; Surgery 16/200)。

  1. Lin CY, Lee LY, Huang SF, Kang CJ, Fan KH, Wang HM, Chen EY, Chen IH, Liao CT, Cheng AJ, Chang JT. Treatment outcome of combined modalities for buccal cancers: unilateral or bilateral neck radiation?  Int J Radiat Oncol Biol Phys. 2008;70(5):1373-1381

(SCI; IF= 4.495; Radiology, nuclear medicine & medical imaging 12/124)。

  1. Lee LY, Wu CM, Wang CC, Yu JS, Liang Y, Huang KH, Lo CH, Hwang TL. Expression of matrix metalloproteinases MMP-2 and MMP-9 in gastric cancer and their relation to claudin-4 expression. Histol Histopathol. 2008;23(5):515-521

(SCI; IF=1.875; Pathology 40/79)。

 

  1. Liao CT, Chang JT, Wang HM, Ng SH, Hsueh C, Lee LY, Lin CH, Chen IH, Huang SF, Cheng AJ, See LC, Yen TC. Does adjuvant radiation therapy improve outcomes in pT1-3N0 oral cavity cancer with tumor-free margins and perineural invasion?  Int J Radiat Oncol Biol Phys. 2008;71(2):371-376

(SCI; IF= 4.495; Radiology, nuclear medicine & medical imaging 12/124)。

  1. Liao CT, Huang SF, Chen IH, Chang JT, Wang HM, Ng SH, Hsueh C, Lee LY, Lin CH, Cheng AJ, Yen TC. When does skin excision allow the achievement of an adequate local control rate in patients with squamous cell carcinoma involving the buccal mucosa?  Ann Surg Oncol. 2008;15(8):2187-2194

(SCI; IF=3.655; Surgery 16/200)。

  1. Chiu CC, Lin CY, Lee LY, Chen YJ, Kuo TF, Chang JT, Liao CT, Wang HM, Yen TC, Shen CR, Liao SK, Cheng AJ. Glucose-regulated protein 78 regulates multiple malignant phenotypes in head and neck cancer and may serve as a molecular target of therapeutic intervention.  Mol Cancer Ther. 2008;7(9):2788-2797

(SCI; IF= 5.579; Oncology 27/213)。

  1. Wu CC, Huang YS, Lee LY, Liang Y, Tang RP, Chang YS, Hsieh LL, Yu JS. Overexpression and elevated plasma level of tumor-associated antigen 90K/Mac-2 binding protein in colorectal carcinoma.  Proteomics Clin Appl. 2008;2(12):1586-1595

(SCI; IF:2.959; Biochemical research methods 28/77)。

  1. Liao CT, Huang SF, Chen IH, Chang JT, Wang HM, Ng SH, Hsueh C, Lee LY, Lin CH, Cheng AJ, Yen TC. Risk stratification of patients with oral cavity squamous cell carcinoma and contralateral neck recurrence following radical surgery.  Ann Surg Oncol. 2009;16(1):159-170

(SCI; IF=3.655; Surgery 16/200)。

  1. Liao CT, Chang JT, Wang HM, Ng SH, Hsueh C, Lee LY, Lin CH, Chen IH, Huang SF, Cheng AJ, See LC, Yen TC. Pretreatment primary tumor suvmax measured by FDG-PET and pathologic tumor depth predict for poor outcomes in patients with oral cavity squamous cell carcinoma and pathologically positive lymph nodes.  Int J Radiat Oncol Biol Phys. 2009;73(3):764-771

(SCI; IF= 4.495; Radiology, nuclear medicine & medical imaging 12/124)。

  1. Chao A, Tsai CN, Hsueh S, Lee LY, Chen TC, Huang SL, Chao FY, Lai CH. Does Epstein-Barr Virus play a role in lymphoepithelioma-like carcinoma of the uterine cervix?  Int J Gynecol Pathol. 2009;28(3):279-285

(SCI; IF=1.437; Pathology 52/79)。

  1. Liao CT, Chang JT, Wang HM, Ng SH, Hsueh C, Lee LY, Lin CH, Chen IH, Huang SF, Cheng AJ, Yen TC. Preoperative [18F] Fluorodeoxyglucose positron emission tomography standardized uptake value of neck lymph nodes predicts neck cancer control and survival rates in patients with oral cavity squamous cell carcinoma and pathologically positive lymph nodes.  Int J Radiat Oncol Biol Phys. 2009;74(4):1054-1061

(SCI; IF= 4.495; Radiology, nuclear medicine & medical imaging 12/124)。

  1. Kuo TT, Chen TC, Lee LY, Lu PH. IgG4-positive plasma cells in cutaneous Rosai-Dorfman disease: an additional immunohistochemical feature and possible relationship to IgG4-related sclerosing disease.  J Cutan Pathol. 2009;36(10):1069-1073

(SCI; IF=1.409; Dermatology 37/61)。

  1. Kang CJ, Chen YJ, Liao CT, Wang HM, Chang JT, Lin CY, Lee LY, Wang TH, Yen TC, Shen CR, Chen IH, Chiu CC, Cheng AJ. Transcriptome profiling and network pathway analysis of genes associated with invasive phenotype in oral cancer.  Cancer Lett. 2009;284(2):131-140

(SCI; IF= 5.992; Oncology 23/213)。

  1. Liao CT, Chang JT, Wang HM, Ng SH, Huang SF, Chen IH, Hsueh C, Lee LY, Lin CH, Cheng AJ, Yen TC. Preoperative [(18)F]-fluorodeoxyglucose positron emission tomography standardized uptake value of neck lymph nodes may aid in selecting patients with oral cavity squamous cell carcinoma for salvage therapy after relapse.  Eur J Nucl Med Mol Imaging. 2009;36(11):1783-1793

(SCI; IF= 5.537; Radiology, nuclear medicine & medical imaging 6/124)。

  1. Fang KH, Kao HK, Cheng MH, Chang YL, Tsang NM, Huang YC, Lee LY, Yu JS, Hao SP, Chang KP. Histological differentiation of primary oral squamous cell carcinomas in an area of betel quid chewing prevalence.  Otolaryngol Head Neck Surg. 2009;141(6):743-749

(SCI; IF= 2.021; Otorhinolaryngology 11/43)。

  1. Kuo TT, Chen TC, Lee LY. Sclerosing angiomatoid nodular transformation of the spleen (SANT): clinicopathological study of 10 cases with or without abdominal disseminated calcifying fibrous tumors, and the presence of a significant number of IgG4+ plasma cells.  Pathol Int.  2009;59(12):844-850

(SCI; IF= 1.425; Pathology 53/79)。

  1. Tam YY, Lee LY, Chang KP. Lymphoepithelial Carcinoma of the Nasolacrimal Duct.  Otolaryngol Head Neck Surg. 2010;142(1):144-145

(SCI; IF= 2.021; Otorhinolaryngology 11/43)。

  1. Chen HH, Lee LY, Chin SC, Chen IH, Liao CT, Huang SF. Carcinoma ex pleomorphic adenoma of soft palate with cavernous sinus invasion.  World J Surg Oncol. 2010;8(1):24

(SCI; IF=1.286; Surgery 118/200)。

  1. Liao CT, Huang SF, Chen IH, Kang CJ, Lin CY, Fan KH, Wang HM, Ng SH, Hsueh C, Lee LY, Tsao CK, Yen TC. Outcome analysis of patients with pN2 oral cavity cancer.  Ann Surg Oncol. 2010;17(4):1118-1126

(SCI; IF=3.655; Surgery 16/200)。

  1. Chou CF, Chin SC, Lee LY, Chen IH, Liao CT, Huang SF. A nasal cavity mucosal melanoma connected by nasolacrimal duct in a patient with multiple co-morbidities: a treatment dilemma.  World J Oncol. 2010;1:182-185
  2. Liao CT, Wang HM, Chang JT, Lin CY, Ng SH, Huang SF, Chen IH, Hsueh C, Lee LY, Lin CH, Cheng AJ, Yen TC. Influence of pathological nodal status and maximal standardized uptake value of the primary tumor and regional lymph nodes on treatment plans in patients with advanced oral cavity squamous cell carcinoma.  Int J Radiat Oncol Biol Phys. 2010;77(2):421-429

(SCI; IF= 4.495; Radiology, nuclear medicine & medical imaging 12/124)。

  1. Ueng SH, Pinto M, Alvarado-Cabrero I, Lee LY, Tavassoli F. Ovarian malignant melanoma: a clinicopathologic study of 5 cases.  Int J Surg Pathol. 2010;18(3):184-192

(SCI; IF=0.782; Surgery 158/200)。

  1. Fang KH, Wang HM, Kang CJ, Lee LY, Huang SF, Lin CY, Chen EY, Chen IH, Liao CT, Chang JT. Treatment results of postoperative radiotherapy on squamous cell carcinoma of the oral cavity: coexistence of multiple minor risk factors results in higher recurrence rates.  Int J Radiat Oncol Biol Phys. 2010;77(4):1024-1029

(SCI; IF= 4.495; Radiology, nuclear medicine & medical imaging 12/124)。

  1. Chang KP, Wu CC, Chen HC, Chen SJ, Peng PH, Tsang NM, Lee LY, Liu SC, Liang Y, Lee YS, Hao SP, Chang YS, Yu JS. Identification of candidate nasopharyngeal carcinoma serum biomarkers by cancer cell secretome and tissue transcriptome analysis: potential usage of cystatin for predicting nodal stage and poor prognosis.  Proteomics. 2010;10(14):2644-2660

(SCI; IF=4.079; Biochemical research methods 13/77)。

 

  1. Lin CY, Chen WH, Liao CT, Chen IH, Chiu CC, Wang HM, Yen TC, Lee LY, Chang JT, Cheng AJ. Positive association of glucose-regulated protein 78 during oral cancer progression and the prognostic value in oral precancerous lesion.  Head Neck. 2010;32(8):1028-1039

(SCI; IF=2.76; Otorhinolaryngology 3/43)。

  1. Hwang TL, Lee LY, Wang CC, Liang Y, Huang SF, Wu CM. Claudin-4 expression is associated with tumor invasion, MMP-2 and MMP-9 expression in gastric cancer.  Exp Ther Med. 2010;1(5):789-797

(SCI; IF=1.28; Medicine, Research& experimental 95/124)。

  1. Huang SF, Chuang WY, Cheng SD, Hsin LJ, Lee LY, Kao HK. A colliding maxillary sinus cancer of adenosquamous carcinoma and small cell neuroendocrine carcinoma - a case report with EGFR copy number analysis.  World J Surg Oncol. 2010;8(1):92

(SCI; IF=1.286; Surgery 118/200)。

  1. Liao CT, Huang SF, Chen IH, Kang CJ, Lin CY, Fan KH, Wang HM, Ng SH, Hsueh C, Lee LY, Lin CH, Yen TC. Tongue and buccal mucosa carcinoma: is there a difference in outcome?  Ann Surg Oncol. 2010;17(11):2984-2991

(SCI; IF=3.655; Surgery 16/200)。

  1. Lin CY, Wang HM, Kang CJ, Lee LY, Huang SF, Fan KH, Chen EY, Chen IH, Liao CT, Chang JT. Primary tumor site as a predictor of treatment outcome for definitive radiotherapy of advanced-stage oral cavity cancers.  Int J Radiat Oncol Biol Phys. 2010;78(4):1011-1019

(SCI; IF= 4.495; Radiology, nuclear medicine & medical imaging 12/124)。

  1. Chen YJ, Liao CT, Chen PJ, Lee LY, Li YC, Chen IH, Wang HM, Chang JT, Chen LJ, Yen TC, Tang CY, Cheng AJ. Downregulation of Ches 1 and other novel genes in oral cancer cells chronically exposed to areca nut extract.  Head Neck. 2011;33(2):257-266

(SCI; IF=2.76; Otorhinolaryngology 3/43)。

  1. Liao CT, Wang HM, Huang SF, Chen IH, Kang CJ, Lin CY, Fan KH, Ng SH, Hsueh C, Lee LY, Lin CH, Yen TC. PET and PET/CT of the neck lymph nodes improves risk prediction in patients with squamous cell carcinoma of the oral cavity.  J Nucl Med. 2011;52(2):180-187 (co-first author)

(SCI; IF= 5.849; Radiology, nuclear medicine & medical imaging 3/124)。

  1. Chang KP, Kao HK, Yen TC, Chang YL, Liang Y, Liu SC, Lee LY, Chang YL, Kang CJ, Chen IH, Liao CT, Yu JS. Overexpression of macrophage inflammatory protein-3αin oral squamous cell carcinoma is associated with nodal metastasis.  Oral Oncol. 2011;47(2):108-113

(SCI; IF=4.286; Dentistry, oral surgery & medicine 3/91)。

  1. Abd El-Hafez YG, Chen CC, Ng SH, Lin CY, Wang HM, Chan SC, Chen IH, Huan SF, Kang CJ, Lee LY, Lin CH, Liao CT, Yen TC. Comparison of PET/CT and MRI for the detection of bone marrow invasion in patients with squamous cell carcinoma of the oral cavity.  Oral Oncol. 2011;47(4):288-295

(SCI; IF=4.286; Dentistry, oral surgery & medicine 3/91)。

  1. Lee LY, Chang KP, Hsu CL, Chen TC, Kuo TT. Small cell neuroendocrine carcinoma of the nasopharynx: report of a rare case lacking association with Epstein - Barr virus.  Int J Surg Pathol.  2011;19 (2):199-202

(SCI; IF=0.782; Surgery 158/200)。

  1. Chen HH, Chen IH, Liao CT, Wei FC, Lee LY, Huang SF. Preoperative circulating C - reactive protein levels predict pathological aggressiveness in oral squamous cell carcinoma.  Clin Otolaryngol. 2011;36(2):147-153

(SCI; IF= 2.627; Otorhinolaryngology 5/43)。

  1. Lee LY, Chen TC, Kuo TT. Simultaneous occurrence of IgG4-related chronic sclerosing dacryoadenitis and chronic sclerosing sialadenitis associated with lymph node involvement and Warthin's tumor.   Int J Surg Pathol. 2011;19 (3):369-372

(SCI; IF=0.782; Surgery 158/200 )。

  1. Chiu CC, Lin CY, Lee LY, Chen YJ, Lu YC, Wang HM, Liao CT, Chang JT, Cheng AJ. Molecular chaperones as a common set of proteins that regulate the invasion phenotype of head and neck cancer. Clin Cancer Res. 2011;17(14):4629-4641

(SCI; IF= 8.738; Oncology 12/213 )。

  1. Chen TD, Lee LY. Rosai-Dorfman disease presenting in the parotid gland with features of IgG4-related sclerosing disease.            Arch Otolaryngol Head Neck Surg. 2011;137(7)705-708 (corresponding author)

(SCI; IF= 2.705; Otorhinolaryngology 4/43)。

  1. Liao CT, Lin CY, Fan KH, Huang SF, Chen IH, Kang CJ, Wang HM, Ng SH, Hsueh C, Lee LY, Lin CH, Yen TC. Identification of a high-risk subgroup of patients with resected pT3 oral cavity cancer in need of postoperative adjuvant therapy.  Ann Surg Oncol. 2011;18(9):2569-2578

(SCI; IF=3.655; Surgery 16/200)。

  1. Lin CY, Lin TY, Wang HM, Huang SF, Fan KH, Liao CT, Chen IH, Lee LY, Li YL, Chen YJ, Cheng AJ, Chang JT. GP96 is over-expressed in oral cavity cancer and is a poor prognostic indicator for patients receiving radiotherapy.  Radiat Oncol. 2011;6(1):136

(SCI; IF= 2.466; Radiology, nuclear medicine & medical imaging 43/124)。

  1. Liao CT, Lee LY, Huang SF, Chen IH, Kang CJ, Lin CY, Fan KH, Wang HM, Ng SH, Yen TC. Outcome analysis of patients with oral cavity cancer and extracapsular spread in neck lymph nodes.  Int J Radiat Oncol Biol Phys. 2011;81(4):930-937

(SCI; IF= 4.495; Radiology, nuclear medicine & medical imaging 12/124)。

  1. Kang CJ, Lin CY, Wang HM, Fan KH, Ng SH, Lee LY, Chen IH, Huang SF, Liao CT, Yen TC. The number of pathologically positive lymph nodes and pathological tumor depth predicts prognosis in patients with poorly differentiated squamous cell carcinoma of the oral cavity.  Int J Radiat Oncol Biol Phys. 2011;81(4):e223-230

(SCI; IF= 4.495; Radiology, nuclear medicine & medical imaging 12/124)。

  1. Kang CJ, Liao CT, Hsueh C, Lee LY, Lin CY, Fan KH, Wang HM, Huang SF, Chen IH, Ng SH, Tsao CK, Huang YC, Yen TC. Outcome analysis of patients with well-differentiated oral cavity squamous cell carcinoma.  Oral Oncol. 2011;47(11):1085-1091

(SCI; IF=4.286; Dentistry, oral surgery & medicine 3/91)。

  1. Chang KP, Yu JS, Chien KY, Lee CW, Liang Y, Liao CT, Yen TC, Lee LY, Huang LL, Liu SC, Chang YS, Chi LM. Identification of PRDX4 and P4HA2 as metastasis-associated proteins in oral cavity squamous cell carcinoma by comparative tissue proteomics of microdissected specimens using iTRAQ technology.  J Proteome Res. 2011;10(11):4935-4947

(SCI; IF=4.173; Biochemical research methods 12/77)。

  1. Chen TD, Chuang HC, Lee LY. Adenoid basal carcinoma of the uterine cervix: clinicopathologic features of twelve cases with reference to CD117 expression.  Int J Gynecol Pathol. 2012;31(1):25-32 (corresponding author)

(SCI; IF=1.437; Pathology 52/79)。

  1. Liao CT, Lin CY, Fan KH, Wang HM, Ng SH, Lee LY, Hsueh C, Chen IH, Huang SF, Kang CJ, Yen TC. Identification of a high-risk group among patients with oral cavity squamous cell carcinoma and pT1-2N0 disease.  Int J Radiat Oncol Biol Phys. 2012 ;82(1):284-290

(SCI; IF= 4.495; Radiology, nuclear medicine & medical imaging 12/124)。

  1. Hsu HH, Lee LY, Chang KP. Pathology quiz case 2.  Arch Otolaryngol Head Neck Surg. 2012;138(1):97-98 (corresponding author)

(SCI; IF= 2.705; Otorhinolaryngology 4/43)。

  1. Hwang TL, Lee LY, Wang CC, Liang Y, Huang SF, Wu CM. CCL7 and CCL21 overexpression in gastric cancer is associated with lymph node metastasis and poor prognosis.  World J Gastroenterol.  2012;18(11): 1249-1256

(SCI; IF=2.787; Gastroenterology & Hepatology 38/79)。

  1. Shen SC, Liao CH, Lo YF, Tsai HP, Kuo WL, Yu CC, Chao TC, Chen MF, Chang HK, Lin YC, Shen WC, Ueng SH, Lee LY, Hsueh S, Huang YT, Chen SC. Favorable outcome of secondary axillary dissection in breast cancer patients with axillary nodal relapse.  Ann Surg Oncol. 2012;19(4):1122-1128

(SCI; IF=3.655; Surgery 16/200)。

  1. Liao CT, Hsueh C, Lee LY, Lin CY, Fan KH, Wang HM, Huang SF, Chen IH, Kang CJ, Ng SH, Tsao CK, Huang YC, Yen TC. Neck dissection field and lymph node density predict prognosis in patients with oral cavity cancer and pathological node metastases treated with adjuvant therapy.  Oral Oncol. 2012;48(4):329-336 (co-first author)

(SCI; IF=4.286; Dentistry, oral surgery & medicine 3/91)。

  1. Liao CT, Fan KH, Lin CY, Wang HM, Huang SF, Chen IH, Kang CJ, Ng SH, Hsueh C, Lee LY, Lin CH, Yen TC. Impact of a second FDG PET scan before adjuvant therapy for the early detection of residual/relapsing tumours in high-risk patients with oral cavity cancer and pathological extracapsular spread.  Eur J Nucl Med Mol Imaging. 2012;39(6):944-955

(SCI; IF= 5.537; Radiology, nuclear medicine & medical imaging 6/124)。

  1. Lee LA, Huang CG, Liao CT, Lee LY, Hsueh C, Chen TC, Lin CY, Fan KH, Wang HM, Huang SF, Chen IH, Kang CJ, Ng SH, Yang SL, Tsao KC, Chang YL, Yen TC.  Human papillomavirus-16 infection in advanced oral cavity cancer patients is related to an increased risk of distant metastases and poor survival.  PLoS One. 2012;7(7):e40767

(SCI; IF=3.057; Multidisciplinary Science 11/62)。

  1. Hsu CL, Chang KP, Lin CY, Chang HK, Wang CH, Lin TL, Liao CT, Tsang NM, Lee LY, Chan SC, Ng SH, Li HP, Chang YS, Wang HM.Plasma Epstein-Barr virus DNA concentration and clearance rate as novel prognostic factors for metastatic nasopharyngeal carcinoma.  Head Neck. 2012;34(8):1064-1070

(SCI; IF=2.76; Otorhinolaryngology 3/43)。

  1. Tsan DL, Lin CY, Kang CJ, Huang SF, Fan KH, Liao CT, Chen IH, Lee LY, Wang HM, Chang JT.  The comparison between weekly and three-weekly cisplatin delivered concurrently with radiotherapy for patients with postoperative high-risk squamous cell carcinoma of the oral cavity.  Radiat Oncol. 2012;7(1):215

(SCI; IF= 2.466; Radiology, nuclear medicine & medical imaging 43/124)。

  1. Liao CT, Lin CY, Fan KH, Hsueh C, Lee LY, Wang HM, Huang SF, Chen IH, Kang CJ, Ng SH, Lin CH, Huang YC, Yen TC.  Outcome analyses of unusual site neck recurrence in oral cavity cancer.  Ann Surg Oncol. 2013;20(1):257-266

(SCI; IF=3.655; Surgery 16/200)。

  1. Chang KC, Lee LY, Wu JH, Liao CT, Chen IH, Kang CJ, Huang SF.  Primary malignant mucosal melanoma-in the oral cavity.  J Taiwan Otolaryngol Head Neck Surg.  2012; 47(4):304-311
  2. Lee LY, Kuo TT. Hyaline globules in a nasopharyngeal carcinoma.  Int J Surg Pathol. 2013;21(1):44

(SCI; IF=0.782; Surgery 158/200)。

  1. Liao CT, Lee LY, Hsueh C, Lin CY, Fan KH, Wang HM, Ng SH, Lin CH, Tsao CK, Chen IH, Chang KP, Huang SF, Kang CJ, Fang KH, Wang YC, Chang YL, Huang YC, Tsai CY, Yen TC. Comparative outcomes in oral cavity cancer with resected pT4a and pT4b.  Oral Oncol. 2013;49(3):230-236

(SCI; IF=4.286; Dentistry, oral surgery & medicine 3/91)。

  1. Chen YJ, Lee LY, Chao YK, Chang JT, Lu YC, Li HF, Chiu CC, Li YC, Li YL, Chiou JF, Cheng AJ.  DSG3 facilitates cancer cell growth and invasion through the DSG3-plakoglobin-TCF/LEF-Myc/Cyclin D1/MMP signaling pathway.  PLoS One. 2013;8(5):e64088

(SCI; IF=3.057; Multidisciplinary Science 11/62)。

  1. Hsu CL, Chan SC, Chang KP, Lin TL, Lin CY, Hsieh CH, Huang SF, Tsang NM, Lee LY, Ng SH, Wang HM.  Clinical scenario of EBV DNA follow-up in patients of treated localized nasopharyngeal carcinoma.  Oral Oncol. 2013;49(6):620-625

(SCI; IF=4.286; Dentistry, oral surgery & medicine 3/91)。

  1. Kao PH, Lee LY, Wu YF, Yang CH, Kuo TT.  A rapidly recurring cutaneous xanthogranuloma-like histiocytic tumor: a diagnostic challenge.  Am J Dermatopathol. 2013;35(4):e60-62

(SCI; IF=1.396; Dermatology 38/61)。

  1. Chao A, Lee LY, Hsueh C, Lin CY, Tsai CL, Chao AS, Lin CT, Chou HH, Chang TC , Wang TH.  Immunohistological analysis of stress-induced phosphoprotein 1 in ovarian cancer patients with low serum cancer antigen 125 levels.  Taiwan. J. Obstet. Gynecol.  2013;52(2) 185-191

(SCI; IF=0.865; Obstetrics & Gynecology 71/80)。

  1. Lee LA, Huang CG, Tsao KC, Liao CT, Kang CJ, Chang KP, Huang SF, Chen IH, Fang TJ, Li HY, Yang SL, Lee LY, Hsueh C, Chen TC, Lin CY, Fan KH, Wang HM, Ng SH, Chang YL, Lai CH, Shih SR, Yen TC. Increasing rates of low-risk human papillomavirus infections in patients with oral cavity squamous cell carcinoma: association with clinical outcomes.  J Clin Virol. 2013;57(4):331-337

(SCI; IF=2.647; Virology 16/33)。

  1. Tseng JR, Ho TY, Lin CY, Lee LY, Wang HM, Liao CT, Yen TC. Clinical outcomes of patients with oral cavity squamous cell carcinoma and retropharyngeal lymph node metastasis identified by FDG PET/CT.  PLoS One. 2013;8(11):e79766

(SCI; IF=3.057; Multidisciplinary Science 11/62)。

  1. Chiu CC, Lee LY, Li YC, Chen YJ, Lu YC, Li YL, Wang HM, Chang JT, Cheng AJ.  Grp78 as a therapeutic target for refractory head-neck cancer with CD24(-)CD44(+) stemness phenotype.  Cancer Gene Ther. 2013;20(11):606-615

(SCI; IF=2.532; Biotechnology & applied microbiology 59/161)。

  1. Chang NJ, Kao DS, Lee LY, Chang JW, Hou MM, Lam WL, Cheng MH.  Sarcomatoid carcinoma in head and neck: a review of 30 years of experience-clinical outcomes and reconstructive results.  Ann Plast Surg. 2013;71 Suppl 1:S1-7

(SCI; IF=1.535; Surgery 104/200)。

  1. Lin CK, Hsu HH, Lee LY, Chang KP.  Nasopharyngeal Hamartoma.  J Taiwan Otolaryngol Head Neck Surg.  2013; 48(4):319-324
  2. Chen TD, Lee LY. A case of renal cell carcinoma metastasizing to invasive ductal breast carcinoma.  J Formos Med Assoc. 2014;113(2):133-136 (corresponding author)

(SCI; IF=2.018; Medicine, general & internal 46/154)。

  1. Fan KH, Lin CY, Kang CJ, Lee LY, Huang SF, Liao CT, Chen IH, Ng SH, Wang HM, Chang JT. Postoperative concomitant chemoradiotherapy improved treatment outcomes of patients with oral cavity cancer with multiple-node metastases but no other major risk factors.  PLoS One. 2014;9(2):e86922

(SCI; IF=3.057; Multidisciplinary Science 11/62)。

  1. Lin CH, Kang CJ, Tsao CK, Wallace CG, Lee LY, Lin CY, Wang HM, Ng SH, Yen TC, Liao CT.  Priority of fibular reconstruction in patients with oral cavity cancer undergoing segmental mandibulectomy.  PLoS One. 2014;9(4):e94315

(SCI; IF=3.057; Multidisciplinary Science 11/62)。

  1. Chuang HC, Kao PH, Huang YL, Lee LY, Kuo TT.  Desmoplastic sebaceoma arising from nevus sebaceus: a new variant.  J Cutan Pathol. 2014;41(6):509-512

(SCI; IF=1.409; Dermatology 37/61)。

  1. Chuang HC, Kang CJ, Lee LY. Sinonasal pure yolk sac tumor: a case report and literature review.  Fetal Pediatr Pathol. 2014;33(3):127-134 (corresponding author)

(SCI; IF=0.514; Pediatrics 112/120)。

  1. Chen KH, Chen TD, Chen CW, Lee LY. Iatrogenic kaposi's sarcoma in nasal cavity: a case report.  World J Surg Oncol. 2014;12(1):172 (corresponding author)

(SCI; IF=1.286; Surgery 118/200)。

  1. Tseng WK, Fang CW, Lee LY.  Goblet cell carcinoid of the appendix: diagnosis, management and literature review.  Journal of Society of Colon and Rectal Surgeons. 2014;25(2):52-62
  2. Liao CT, Wallace CG, Lee LY, Hsueh C, Lin CY, Fan KH, Wang HM, Ng SH, Lin CH, Tsao CK, Chen IH, Huang SF, Kang CJ, Yen TC.  Clinical evidence of field cancerization in patients with oral cavity cancer in a betel quid chewing area.  Oral Oncol. 2014;50(8):721-731

(SCI; IF=4.286; Dentistry, oral surgery & medicine 3/91)。

  1. Hwang TL, Lee LY, Cheb TC, Thorat A, Hsu JT, Yeh CN, Yeh TS, Jan YY.  2014 Aug.  Prognosis of ductal adenocarcinoma of pancreatic head with overexpression of CD44.  Formosan Journal of Surgery. 2014;47(4):138-144
  2. Huang CG, Lee LA, Tsao KC, Liao CT, Yang LY, Kang CJ, Chang KP, Huang SF, Chen IH, Yang SL, Lee LY, Hsueh C, Chen TC, Lin CY, Fan KH, Chang TC, Wang HM, Ng SH, Yen TC. Human papillomavirus 16/18 E7 viral loads predict distant metastasis in oral cavity squamous cell carcinoma.  J Clin Virol. 2014;61(2):230-236

(SCI; IF=2.647; Virology 16/33)。

  1. Kang C, Lin C, Yang L, Ho T, Lee LY, Fan K, Wang H, Huang S, Chang K, Fang K, Ng S, Liao C, Yen T.*  Positive clinical impact of an additional PET/CT scan before adjuvant radiotherapy or concurrent chemoradiotherapy in patients with advanced oral cavity squamous cell carcinoma.  J Nucl Med. 2015;56 (1)22-30

(SCI; IF= 5.849; Radiology, nuclear medicine & medical imaging 3/124)。

  1. Young CK, Lin WN, Lee LY, Lee LA, Hsin LJ, Liao CT, Li HY, Chen IH, Fang TJ.  Laryngoscopic characteristics in vocal leukoplakia: Inter-rater reliability and correlation with histology grading.  Laryngoscope 2015;125(2):E62-66

(SCI; IF=2.272; Otorhinolaryngology 9/43)。

  1. Lu YC, Chang JT, Huang YC, Huang CC, Chen WH, Lee LY, Huang BS, Chen YJ, Li HF, Cheng AJ.  Combined determination of circulating miR-196a and miR-196b levels produces high sensitivity and specificity for early detection of oral cancer.  Clin Biochem. 2015;48(3):115-121

(SCI; IF=2.382; Medical laboratory technology 9/29)。

  1. Cheng NM, Fang YH, Lee LY, Chang JT, Tsan DL, Ng SH, Wang HM, Liao CT, Yang LY, Hsu CH, Yen TC.  Zone-size nonuniformity of 18F-FDG PET regional textural features predicts survival in patients with oropharyngeal cancer.  Eur J Nucl Med Mol Imaging. 2015;42(3):419-428

(SCI; IF= 5.537; Radiology, nuclear medicine & medical imaging 6/124)。

  1. Chi CL, Kuo TT, Lee LY.  Oncocytic lipoadenoma: a rare case of parotid gland tumor and review of the literature.  J Pathol Transl Med. 2015;49(2):144-147 (corresponding author)
  2. Hsieh CE, Lin CY, Lee LY, Wang HM, Chang JT, Fan KH, Huang BS, Liao CT, Yen TC, Fang KH, Tsang NM.  Postoperative radiotherapy with or without concurrent chemotherapy for salivary gland carcinoma.  Therapeut Radiol Oncol. 2015;22(2):89-101
  3. Lee LY, Chen YJ, Lu YC, Liao CT, Chen IH, Chang JT, Huang YC, Chen WH, Huang CC, Tsai CY, Cheng AJ.  Fascin is a circulating tumor marker for head and neck cancer as determined by a proteomic analysis of interstitial fluid from the tumor microenvironment.  Clin Chem Lab Med. 2015;53(10):1631-1641 (co-first author)

(SCI; IF=3.017; Medical laboratory technology 5/29)。

  1. Liao CT, Fan KH, Kang CJ, Lin CY, Chang JT, Tsang NM, Huang BS, Chao YK, Lee LY, Hsueh C, Wang HM, Liau CT, Hsu CL, Hsieh CH, Ng SH, Lin CH, Tsao CK, Fang TJ, Huang SF, Chang KP, Yen TC.  Clinical outcomes of patients with resected oral cavity cancer and simultaneous second primary malignancies.  PLoS One. 2015;10(9):e0136918

(SCI; IF=3.057; Multidisciplinary Science 11/62)。

  1. Hsu CL, Kuo YC, Huang Y, Huang YC, Lui KW, Chang KP, Lin TL, Fan HC, Lin AC, Hsieh CH, Lee LY, Wang HM, Li HP, Chang YS.  Application of a patient-derived xenograft model in cytolytic viral activation therapy for nasopharyngeal carcinoma.  Oncotarget. 2015;6(31):31323-31334

(SCI; IF= 5.008; Oncology 36/213)。

  1. Adel M, Kao HK, Hsu CL, Huang JJ, Lee LY, Huang Y, Browne T, Tsang NM, Chang YL, Chang KP.  Evaluation of lymphatic and vascular Invasion in relation to clinicopathological factors and treatment outcome in oral cavity squamous cell carcinoma.  Medicine (Baltimore).  2015;94(43):e1510

(SCI; IF=2.133; Medicine, general & internal 40/154)。

  1. Lee LA, Huang CG, Tsao KC, Liao CT, Kang CJ, Chang KP, Huang SF, Chen IH, Fang TJ, Li HY, Yang SL, Lee LY, Hsueh C, Lin CY, Fan KH, Chang TC, Wang HM, Ng SH, Yen TC.  Human papillomavirus infections are common and predict mortality in a retrospective cohort study of Taiwanese patients with oral cavity cancer.  Medicine (Baltimore). 2015;94(47):e2069

(SCI; IF=2.133; Medicine, general & internal 40/154)。

  1. Wang HM, Cheng NM, Lee LY, Dean Fang YH, Chang JT, Tsan DL, Ng SH, Liao CT, Yang LY, Yen TC.  Heterogeneity of 18 F-FDG PET combined with expression of EGFR may improve the prognostic stratification of advanced oropharyngeal carcinoma.  Int J Cancer. 2016 ;138(3):731-738

(SCI; IF= 5.531; Oncology 29/213)。

  1. Liao CT, Chen SJ, Lee LY, Hsueh C, Yang LY, Lin CY, Fan KH, Wang HM, Ng SH, Lin CH, Tsao CK, Chen IH, Chang KP, Huang SF, Kang CJ, Chen HC, Yen TC.  An ultra-deep targeted sequencing gene panel improves the prognostic stratification of patients with advanced oral cavity squamous cell carcinoma.  Medicine (Baltimore). 2016 ;95(8):e2751

(SCI; IF=2.133; Medicine, general & internal 40/154)。

  1. Hsieh CE, Lin CY, Lee LY, Yang LY, Wang CC, Wang HM, Chang JT, Fan KH, Liao CT, Yen TC, Fang KH, Tsang YM.  Adding concurrent chemotherapy to postoperative radiotherapy improves locoregional control but not overall survival in patients with salivary gland adenoid cystic carcinoma-a propensity score matched study.  Radiat Oncol. 2016;11(1):47

(SCI; IF= 2.466; Radiology, nuclear medicine & medical imaging 43/124)。

  1. Adel M, Liao CT, Lee LY, Hsueh C, Lin CY, Fan KH, Wang HM, Ng SH, Lin CH, Tsao CK, Huang SF, Kang CJ, Fang KH, Wang YC, Chang KP, Fang TJ, Yang LY, Yen TC.  Incidence and outcomes of patients with oral cavity squamous cell carcinoma and fourth primary tumors: a long-term follow-up study in a betel quid chewing endemic area.  Medicine (Baltimore). 2016;95(12):e2950

(SCI; IF=2.133; Medicine, general & internal 40/154)。

  1. Fang TJ, Lin WN, Lee LY, Young CK, Lee LA, Chang KP, Liao CT, Li HY, Yen TC.  Classification of vocal fold leukoplakia by clinical scoring.  Head Neck. 2016;38:Suppl 1:E1998-2020

(SCI; IF=2.76; Otorhinolaryngology 3/43)。

  1. Liao CT, Kang CJ, Lee LY, Hsueh C, Lin CY, Fan KH, Wang HM, Ng SH, Lin CH, Tsao CK, Fang TJ, Huang SF, Chang KP, Chang YL, Yang LY, Yen TC.  Association between multidisciplinary team care approach and survival rates in patients with oral cavity squamous cell carcinoma.  Head Neck. 2016; 38 Suppl 1:E1544-1553

(SCI; IF=2.76; Otorhinolaryngology 3/43)。

  1. Li YC, Chang JT, Chiu C, Lu YC, Li YL, Chiang CH, You GR, Lee LY, Cheng AJ.  Areca nut contributes to oral malignancy through facilitating the conversion of cancer stem cells.  Mol Carcinog. 2016;55(5):1012-1023

(SCI; IF= 4.722; Oncology 42/213)。

  1. Lin CY, Lee LY, Kuo TT.  Malignant clear cell acanthoma: report of a rare case of clear cell acanthoma-like tumor with malignant features.  Am J Dermatopathol. 2016 ;38(7):553-556

(SCI; IF=1.396; Dermatology 38/61)。

  1. Lapke N, Lu YJ, Liao CT, Lee LY, Lin CY, Wang HM, Ng SH, Chen SJ, Yen TC.  Missense mutations in the TP53 DNA-binding domain predict outcomes in patients with advanced oral cavity squamous cell carcinoma.  Oncotarget. 2016;7(28):44194-44210

(SCI; IF= 5.008; Oncology 36/213)。

  1. Wang HM, Lin TL, Kuo YC, Li HP, Chang KP, Lin CY, Fan HC, Lin AC, Hsieh CH, Tsang NM, Lee LY, Chan SC, Lui KW, Chang YS, Hsu CL.  Correlation between overall survival and differential plasma and tissue tumor marker expression in nasopharyngeal carcinoma patients with different sites of organ metastasis.  Oncotarget. 2016;7(33):53217-53229

(SCI; IF= 5.008; Oncology 36/213)。

  1. Huang BS, Chen WY, Hsieh CE, Lin CY, Lee LY, Fang KH, Tsang NM, Kang CJ, Wang HM, Chang JT.  Outcomes and prognostic factors for surgery followed by modern radiation therapy in parotid gland carcinomas.  Jpn J Clin Oncol. 2016; 46(9):832-838

(SCI; IF=1.889; Oncology 160/213)。

  1. Chiang CH, Wu CC, Lee LY, Li YC, Liu HP, Hsu CW, Lu YC, Chang JT, Cheng AJ.  Proteomics analysis reveals involvement of Krt17 in areca nut-induced oral carcinogenesis.  J Proteome Res. 2016;15(9):2981-2997

(SCI; IF=4.173; Biochemical research methods 12/77)。

  1. Lin CY, Chao A, Wang TH, Lee LY, Yang LY, Tsai CL, Wang HS, Lai CH.  Nucleophosmin/B23 is a negative regulator of estrogen receptor α expression via AP2γ in endometrial cancer cells.  Oncotarget. 2016;7(37):60038-60052

(SCI; IF= 5.008; Oncology 36/213)。

  1. Wang HM, Liao CT, Yen TC, Chen SJ, Lee LY, Hsieh CH, Lin CY, Ng SH.  Clues toward precision medicine in oral squamous cell carcinoma: utility of next-generation sequencing for the prognostic stratification of high-risk patients harboring neck lymph node extracapsular extension.  Oncotarget. 2016;7(39):63082-63092

(SCI; IF= 5.008; Oncology 36/213)。

  1. Liao CT, Chen HN, Wen YW, Lee SR, Ng SH, Liu TW, Tsai ST, Tsai MH, Lin JC, Lou PJ, Wang CP, Chu PY, Leu YS, Tsai KY, Terng SD, Chen TM, Wang CH, Chien CY, Chen WC, Lee LY, Lin CY, Wang HM, Lin CH, Fang TJ, Huang SF, Kang CJ, Chang KP, Yang LY, Yen TC.  Association between the diagnosis-to-treatment interval and overall survival in Taiwanese patients with oral cavity squamous cell carcinoma.  Eur J Cancer. 2017;72:226-234

(SCI; IF= 6.163; Oncology 22/213)。

  1. Li YL, Chang JT, Lee LY, Fan KH, Lu YC, Li YC, Chiang CH, You GR, Chen HY, Cheng AJ.   GDF15 contributes to radioresistance and cancer stemness of head and neck cancer by regulating cellular reactive oxygen species via a SMAD-associated signaling pathway.  Oncotarget. 2017;8(1):1508-1528

(SCI; IF= 5.008; Oncology 36/213)。

  1. Liao CT, Wen YW, Lee SR, Liu TW, Tsai ST, Tsai MH, Lin JC, Lou PJ, Chu PY, Leu YS, Tsai KY, Terng SD, Chen TM, Wang CH, Chien CY, Chen WC, Lee LY, Lin CY, Wang HM, Ng SH, Lin CH, Fang TJ, Huang SF, Kang CJ, Chang KP, Yang LY, Yen TC; Taiwan Oral Cancer Advisory Group.  Clinical Outcomes of Taiwanese Patients with cT4 Oral Cavity Squamous Cell Carcinoma: Toward the Identification of the Optimal Initial Treatment Approach for cT4b Patients.  Ann Surg Oncol. 2017;24(3):785-793

(SCI; IF=3.655; Surgery 16/200)。

  1. Kuo KL, Lee LY, Kuo TT.  Solitary cutaneous focal mucinosis: A clinicopathological study of 11 cases of soft fibroma-like cutaneous mucinous lesions.  J Dermatol. 2017;44(3):335-338

(SCI; IF=1.577; Dermatology 30/61 )。

 

B. Books:

1. 總校閱 李麗玉, 原著:Mitchell, Kumar, Abbas, Fausto. Robbins病理學手冊 第七版 Elsevier(Singapore) Pte Ltd.合記圖書出版社. 2008.

 

Presentations:

  1. Lee LY, Hsueh S, Hsueh C.  Low- grade endometrial stromal sarcoma with metastasis to left ovary and small intestine. Annual Meeting, Taiwan Society of Pathology, Tungs’ Taichung MetroHarbor Hospital. Nov 24, 2002. (Oral Presentation)
  2. Lee LY, Chang JT, Cheng AJ. Enhancement of radiosensitivity of nasopharyngeal cancer cells by knockdown the expression of gp96 or GDF-15. International Meeting on Innovative Approaches in Head and Neck Oncology. Barcelona, February 22-24, 2006. (poster)
  3. Lee LY, Kuo TT. Simultaneous occurrence of IgG4-related chronic sclerosing dacryoadenitis and chronic sclerosing sialadenitis in a patient also with involvement of lymph node and Warthin’s tumor. The 2nd Japanese-Taiwan Conjoint Slide Conference. Fukuoka, Japan. September 6, 2008. (Oral Presentation)
  4. Lee LY, Ueng SH, Jung SM. A clinicopathological study of appendiceal endometriosis in a Taiwan medical center. The 7th Asia Pacific IAP Congress (APIAP 2011). Taipei, Taiwan. May 20-24, 2011. (poster)

 

Honor &/or Awards:

Honoray Teacher of Chang Gung University Medical student,     Linkou Chang Gung Memorial Hospital (2005-03-1~2012-12-31)

Honoray Teacher of post- graudate year (PGY) student,

Linkou Chang Gung Memorial Hospital (2012-07-1~2017-06-30)

Honoray Teacher of graudate year student,

Linkou Chang Gung Memorial Hospital (2015-06-1~2016-05-31)

Honoray Teacher, Linkou Chang Gung Memorial Hospital (2010)

Top ten Honoray Teacher, Linkou Chang Gung Memorial Hospital (2014)

 

Other Information:

  1. Teaching the Pathology Laboratory course for the 4th year medical students in 2002-2016.
  2. Lectures on Pathology for 4th year medical students in 2003-2013.
  3. Lectures on General Pathology for the 3rd year medical technology students in 2003-2016.
  4. Lectures on General Pathology for the 3rd year occupational therapy students in 2003-2016.
  5. 林口長庚開刀房委員會委員(2011-2013)
  6. 林口長庚病理組織委員會委員(2014)
  7. 林口長庚解剖病理專科醫師訓練計畫主持人(2015-2016)

 

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